Peptides

Transdermal Peptide - 1 mg

  • Cat.Number : AS-62066
  • Availability :
    In stock

Quantity

This short synthetic peptide facilitates efficient transdermal protein drug delivery through intact skin. Co-administration of the peptide and insulin to the abdominal skin of diabetic rats results in elevated systemic levels of insulin and suppresses serum glucose levels. This peptide creates a transient opening in the skin barrier to enable macromolecular drugs to reach systemic circulation.

Specifications

Chemistry
Sequence one letter code
  • ACSSSPSKHCG
Sequence three letter code
  • H-Ala-Cys-Ser-Ser-Ser-Pro-Ser-Lys-His-Cys-Gly-OH
Molecular Formula
  • C40H64N14O16S2
Molecular Mass/ Weight
  • 1063.2
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use

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Citations

Effective siRNA delivery and target mRNA degradation using an amphipathic peptide to facilitate pH-dependent endosomal escape

Biochem J.  . 2011 Apr 15 ; 435(2) 475 | DOI : 10.1042/BJ20101021

  • R. Bartz

References

Transdermal protein delivery by a coadministered peptide identified via phage display.

Nat Biotechnol. . 2006 Mar 26 ; 24(4) 455 | DOI : 10.1038/nbt1193

  • Y. Chen
  • et al