Peptides

Transportan - 1 mg

$256.00
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  • Cat.Number : AS-61256
  • Availability :
    In stock

Quantity

This peptide is Transportan (TP), an amphipathic antimicrobial cell-penetrating peptide. It is a 27 amino acids (aa) long chimeric peptide containing 12 aa from the amino-terminal part of the neuropeptide galanin and the 14 aa long mastoparan (Vespula lewisii wasp venom), connected via a lysine residue. TP reveals some characteristic features of both galanin and mastoparan since it inhibits the binding of galanin to GALR-1 receptor as well as modulates the activity of G proteins due to the inhibition of GTPase activity.

Specifications

Chemistry
Sequence one letter code
  • GWTLNSAGYLLGKINLKALAALAKKIL
Sequence three letter code
  • Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Lys-Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Lys-Ile-Leu
Molecular Formula
  • C134H226N34O33
Molecular Mass/ Weight
  • 2841.7
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Synthetic construct

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References

Protein and siRNA delivery by transportan and transportan 10 into colorectal cancer cell lines.

Folia Histochem Cytobiol . 2014 Dec 16 ; 52(4) 270 | DOI : 10.5603/FHC.a2014.0035

  • PM. Wierzbicki
  • et al