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Peptides

TRP-2, Tyrosinase-related Protein 2 (180-188) - 1 mg

$128.00
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  • Cat.Number : AS-61058
  • Availability :
    In stock

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This peptide is derived from tyrosinase-related protein 2 (TRP2) residues 180-188. TRP2 belongs to the melanocyte differentiation antigens and has been implicated as a target for immunotherapy of human as well as murine melanoma. Studies show that this TRP2 derived peptide can bind to mouse and human MHC class I molecules. Immunization with TRP2 peptide loaded dendritic cells (DCs) results in effective induction of antitumor immunity.

Specifications

Chemistry
Sequence one letter code
  • SVYDFFVWL
Sequence three letter code
  • H-Ser-Val-Tyr-Asp-Phe-Phe-Val-Trp-Leu-OH
Molecular Formula
  • C61H78N10O14
Molecular Mass/ Weight
  • 1175.4
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human, mouse

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References

Mechanism of Activation of NDR (Nuclear Dbf2-related) Protein Kinase by the hMOB1 Protein

J Biol Chem . 2004 Aug 01 ; 279(34) 35228 | DOI : https://doi.org/10.1074/jbc.M404542200

  • S. Bichsel
  • et al

Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway

The EMBO J. . 1999 Jun 01 ; 18(11) 3024 | DOI : https://doi.org/10.1093/emboj/18.11.3024

  • J. Park
  • et al