IMG-EN-AS-60981-01.jpg
Peptides

[Des-octanoyl]-Ghrelin, rat, mouse - 1 mg

$310.00
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  • Cat.Number : AS-60981
  • Availability :
    In stock

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Des-octanoyl (or Des-acyl) Ghrelin is the unacylated precursor peptide to Ghrelin. Des-octanoyl Ghrelin is converted to Ghrelin by the enzymic addition of an octanyl group. Studies indicate that the amount of Des-octanoyl Ghrelin in the circulation is approximately 20 fold higher than that of Ghrelin. Des-octanoyl Ghrelin is not an agonist of the Ghrelin growth hormone receptor 1a (GHSR1a).

Specifications

Chemistry
Sequence one letter code
  • GSSFLSPEHQKAQQRKESKKPPAKLQPR
Sequence three letter code
  • H-Gly-Ser-Ser-Phe-Leu-Ser-Pro-Glu-His-Gln-Lys-Ala-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg-OH
CAS registry number
  • 307950-60-3
Molecular Formula
  • C139H231N45O41
Molecular Mass/ Weight
  • 3188.8
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • rat

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Citations

Ghrelin treatment protects lactotrophs from apoptosis in the pituitary of diabetic rats.

Mol Cell Endocrinol . 2009 Jun 18 ; 309(1-2) 67 | DOI : 10.1016/j.mce.2009.06.006

  • M. Granado

References

Hypotensive effects of ghrelin receptor agonists mediated through a novel receptor

Br J Pharmacol  . 2014 Mar 01 ; 171(5) 1275 | DOI : https://doi.org/10.1111/bph.12527

  • B. Callaghan
  • et al