Peptides

[Lys3]-Bombesin - 5 mg

$237.00
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  • Cat.Number : AS-22838
  • Availability :
    In stock

Quantity

PET (Positron Emission Tomography) imaging of [Lys3]-bombesin is able to detect gastrin-releasing peptide receptor (GRPR) positive prostate cancer. An immunoconjugate of [Lys3]-bombesin and corresponding monoclonal antibody can specifically induce (CD64)-dependent monocyte and neutrophil-mediated lysis of small cell carcinoma.

Specifications

Chemistry
Sequence one letter code
  • Pyr-QKLGNQWAVGHLM-NH2
Sequence three letter code
  • Pyr-Gln-Lys-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2
CAS registry number
  • 66839-66-5
Molecular Formula
  • C71H110N22O18S
Molecular Mass/ Weight
  • 1592
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • toad

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References

microPET and Autoradiographic Imaging of GRP Receptor Expression with 64Cu-DOTA-[Lys3]Bombesin in Human Prostate Adenocarcinoma Xenografts

J Nucl Med . 2004 Aug 01 ; 45(8) 1390 | DOI : PMID: 15299066

  • X. Chen
  • et al

Design, Synthesis, and Initial Evaluation of High-Affinity Technetium Bombesin Analogues

Bioconjug Chem . 1998 Feb 18 ; 9(2) 218 | DOI : https://doi.org/10.1021/bc9701959

  • K. Baidoo
  • et al