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Peptides

Magainin 2

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  • Cat.Number : AS-20639
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Magainin 2 assumes an amphiphilic helix when bound to acidic phospholipids, forming a pore composed of a dynamic, peptide-lipid supramolecular complex.

Specifications

Chemistry
Sequence one letter code
  • GIGKFLHSAKKFGKAFVGEIMNS
Sequence three letter code
  • H-Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Lys-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-Asn-Ser-OH
CAS registry number
  • 108433-95-0
Molecular Formula
  • C114H180N30O29S
Molecular Mass/ Weight
  • 2467.1
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Xenopus

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Citations

Use of a real-time polymerase chain reaction thermocycler to study bacterial cell permeabilization by antimicrobial peptides

Anal Biochem . 2008 Jul 15 ; 381(2) 279 | DOI : 10.1016/j.ab.2008.07.005

  • CYM. Okumura

Importance of the disulfide bridges in the antibacterial activity of human hepcidin

Peptides. . 2012 Jun 15 ; 36(2) 303 | DOI : 10.1016/j.peptides.2012.06.001

  • A. Hocquellet

Structure–activity relationship of human liver-expressed antimicrobial peptide 2.

Peptides . 2010 Jan 31 ; 31(1) 58 | DOI : 10.1016/j.peptides.2009.10.006

  • A. Hocquellet

References

Characterization of unique amphipathic antimicrobial peptides from venom of the scorpion Pandinus imperator

Biochem J . 2001 Sep 24 ; 359(1) 35 | DOI : https://doi.org/10.1042/bj3590035

  • G. Corzo
  • et al

Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor

PNAS . 1987 Aug 01 ; 84(15) 5449 | DOI : https://doi.org/10.1073/pnas.84.15.5449

  • M. Zasloff
  • et al

Modulation of Magainin 2−Lipid Bilayer Interactions by Peptide Charge

Biochem . 1997 Feb 25 ; 36(8) 2104 | DOI : https://doi.org/10.1021/bi961870p

  • K. Matsuzaki
  • et al