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Peptides  >  Signal Transduction Peptides  >>  IRBP, Interphotoreceptor Retinoid Binding Protein Fragment

Product Name IRBP, Interphotoreceptor Retinoid Binding Protein Fragment
Size 1 mg
Catalog # AS-60183-1
US$ $121
Purity % Peak Area By HPLC ≥ 95%

This 20-residue peptide, a major pathogenic T-cell epitope (161180), is present in the first homologous repeat of the interphotoreceptor retinoid binding protein peptide (IRBP). It has been shown to induce posterior uveitis (EAU).

Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
Storage -20C
References Ref: Sonoda, K. et al. J. Immunol. 171, 2652 (2003); Read, RW. and SR. Barnum, ARVO Meeting Abstracts 43, 2281 (2002); Silver, P. et al. Invest. Ophthal. Vis. Sci. 36, 946 (1995); Karabekian, Z. et al. Invest. Ophthalmol. Vis. Sci. 46, 3769 (2005).
Molecular Weight 2209.5
(One-Letter Code)
(Three-Letter Code)
H - Ser - Gly - Ile - Pro - Tyr - Ile - Ile - Ser - Tyr - Leu - His - Pro - Gly - Asn - Thr - Ile - Leu - His - Val - Asp - OH
Product Citations Zhang, Z. et al. (2012). Low dose rapamycin exacerbates autoimmune experimental uveitis. Plos One doi:10.1371/journal.pone.0036589

An, F. et al. Invest Ophthalmol Vis Sci 50, 3778 (2009).

Tan, Jung. et al. J Immunol 178, 5578 (2007).

Pennesi, G. et al. J Clin Invest 111, 1171 (2003).
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