IMG-EN-AS-22516-01.jpg
Peptides

PACAP (6-38), amide, human, ovine, rat

$210.00
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  • Cat.Number : AS-22516
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    In stock

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This peptide is a potent antagonist of PACAP 38 and is much more potent and selective than PACAP (6-27) in the inhibition of PACAP-27 stimulated pituitary adenylate cyclase. The Ki values for the inhibition of the enzyme are 7nM and 150 nM, respectively.

Specifications

Chemistry
Sequence one letter code
  • FTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNK-NH2
Sequence three letter code
  • H-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2
CAS registry number
  • 143748-18-9
Molecular Formula
  • C182H300N56O45S
Molecular Mass/ Weight
  • 4025
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human, ovine, rat

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References

Structural requirements for the occupancy of pituitary adenylate-cyclase-activating-peptide (PACAP) receptors and adenylate cyclase activation in human neuroblastoma NB-OK-1 cell membranes

Eur J Biochem . 1992 Jul 01 ; 207(1) 239 | DOI : https://doi.org/10.1111/j.1432-1033.1992.tb17043.x

  • P. Robberecht
  • et al