Peptides

b-casomorphin (1-7), bovine - 1 mg

  • Cat.Number : AS-61124
  • Availability :
    In stock

Quantity

b-Casomorphin-7 is a milk opioid peptide derived from fragment 60-66 of bovine beta-Casein. It strongly stimulates mucin secretion in the rat jejunum through a nervous pathway and mu-opioid receptor activation. The presence of the Tyr-Pro aromatic sequence makes the peptide selective for the mu receptor while the high contents of proline residues in the sequence makes the peptide resistant to degradation by gastrointestinal enzymes.

Specifications

Chemistry
Sequence one letter code
  • YPFPGPI
Sequence three letter code
  • H-Tyr-Pro-Phe-Pro-Gly-Pro-Ile-OH
CAS registry number
  • 72122-62-4
Molecular Formula
  • C41H55N7O9
Molecular Mass/ Weight
  • 790
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Bovine

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References

b-Casomorphin-7 regulates the secretion and expression of gastrointestinal mucins through a -opioid pathway

Am J Physiol - Gastrointestinal Liver Physiol . 2005 Dec 15 ; 290 G1105 | DOI : 10.1152/ajpgi.00455.2005.

  • S. Zoghbi
  • et al

Milk Bioactive Peptides and β-Casomorphins Induce Mucus Release in Rat Jejunum

Am J Nutrition . 2003 Nov 01 ; 133(11) 3499 | DOI : https://doi.org/10.1093/jn/133.11.3499

  • A. Trompette
  • et al

Novel Opioid Peptides Derived from Casein (β-Casomorphins). I. Isolation from Bovine Casein Peptone

Hoppe Seylers Z Physiol Chem . 1979 Sep 01 ; 360(9) 1211 | DOI : 10.1515/bchm2.1979.360.2.1211

  • V. Brantl
  • et al