This peptide sequence is found in residues 1 to 21 of the histone H3K9(Ac) . H3K9(Ac) is highly localized to the 5’ region of transcription start sites in human genes. Localization of H3K9(Ac) to the transcriptionally active 5’ region of human genes suggests this peptide is essential for transcription initiation and elongation.
Midorikawa, K. et al. Biochem Biophys Res Commun333, 1073 (2005).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Ala - Arg - Thr - Lys - Gln - Thr - Ala - Arg - Lys(Ac) - Ser - Thr - Gly - Gly - Lys - Ala - Pro - Arg - Lys - Gln - Leu - Ala - OH