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Peptides  >  Orexins  >>  Orexin B, human

Product Name Orexin B, human
Size 1 mg
Catalog # AS-65573
US$ $263
Purity Peak Area by HPLC ≥95%
Description

Orexins are synthesized by posterolateral neurons in hypothalamus. They bind to orexin-1 (OxR1) and orexin 2 (OxR2) receptors. Orexin A can bind to both OxR1 and OxR2 while Orexin B can associate with OxR2 only. Both Orexins are involved in the regulation of arousal and sleep states, energy homeostasis, and autonomic central control.

Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
Storage 20C
References 1. Martynska L., et.al., Neuroendocr Lett 4(26), 289-292 (2005).
2. Ebrahim I.O., et.al., J of Royl Soc of Med95, 227-230 (2002).
3. Ramanjaneya M., et.al., Endocrinology151 (7), 3169-3180 (2010).
Molecular Weight 2899.6
Sequence
(One-Letter Code)
RSGPPGLQGRLQRLLQASGNHAAGILTM-NH2
Sequence
(Three-Letter Code)
Arg - Ser - Gly - Pro - Pro - Gly - Leu - Gln - Gly - Arg - Leu - Gln - Arg - Leu - Leu - Gln - Ala - Ser - Gly - Asn - His - Ala - Ala - Gly - Ile - Leu - Thr - Met - NH2
     
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