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Peptides  >  Mitochondrial Peptides  >>  SHLP1 (Small humanin-like peptide 1)

Product Name SHLP1 (Small humanin - like peptide 1)  NEW
H - MCHWAGGASNTGDARGDVFGKQAG - OH
Size 1 mg
Catalog # AS-65588
US$ $381
Purity % Peak Area By HPLC ≥ 95%
Description

Recent advances in high-resolution sequencing have led to the discovery of unique peptides derived from mitochondrial genome.1-2 Currently 8 peptides are identified: humanin, mitochondrial open reading frame of the 12S tRNA-c (MOTS-c), and six small humanin-like peptides (SHLP1-6). 1-2 All of these peptides are released into cytosol from mitochondria and associate with increased longevity and cell viability, reduced apoptosis, and other beneficial functions. 1-3 MOTS-c was found to reduce insulin resistance, decrease obesity, and promote homeostasis. 3

Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
Storage -20C
References 1. Cobb L. J. et al., AGING 8 (4), 796-808 (2016).
2. Okada A. K. et al., Sci Reports 7 (7802), 1-10 (2017).
3. Lee C., et al., Cell Met 21, 443-454 (2015).
Molecular Weight 2393.6
Sequence
(One-Letter Code)
H-MCHWAGGASNTGDARGDVFGKQAG-OH
Sequence
(Three-Letter Code)
NH2 - Met - Cys - His - Trp - Ala - Gly - Gly - Ala - Ser - Asn - Thr - Gly - Asp - Ala - Arg - Gly - Asp - Val - Phe - Gly - Lys - Gln - Ala - Gly - COOH
     
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