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Peptides  >  SARS-CoV2/COVID-19 Peptides  >>  Spike protein (S2) SARS-CoV-2 substrate

Product Name Spike protein (S2) SARS - CoV - 2 substrate
QXL520 - SKPSKRSFIED - K(5 - FAM) - NH2
Size 0.1 mg
Catalog # AS-65601
US$ $205
Purity >95%
Description

This peptide sequence represents a second furin-like cleavage site of the Spike (S) protein also thought to participate in the process of viral entry into host cell. The sequence at the S2 site (KR↓SF) contains two basic residues (P1 and P2) and a hydrophobic P3 residue. This site is identical between the SARS-CoV-2 and SARS-CoV.
This peptide has been labeled with QXL520 and 5-FAM.

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20 C
References Coutard B, et al. The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade. Antiviral Res. 2020 Apr;176:104742. doi: 10.1016/j.antiviral.2020.104742.
Molecular Weight 2270.4
Sequence
(One-Letter Code)
QXL520-SKPSKRSFIED-K(5-FAM)-NH2
Sequence
(Three-Letter Code)
QXL520 - Ser - Lys - Pro - Ser - Lys - Arg - Ser - Phe - Ile - Glu - Asp - Lys(5 - FAM) - OH
     
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