IMG-EN-AS-60708-01.jpg
Peptides

ACTH (1-17) - 1 mg

$100.00
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  • Cat.Number : AS-60708
  • Availability :
    In stock

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ACTH (1–17), and aMSH (a-Melanotropin), both derived from POMC (proopiomelanocortin) are involved in melanogenesis. However, ACTH (1-17) has been found to be more potent in malanogenesis in human malanocytes. Both ACTH (1-17) and aMSH also increase dendricity, and proliferation in follicular melanocytes.

Specifications

Chemistry
Sequence one letter code
  • SYSMEHFRWGKPVGKKR
Sequence three letter code
  • H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-OH
CAS registry number
  • 7266-47-9
Molecular Formula
  • C95H145N29O23S
Molecular Mass/ Weight
  • 2093.5
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human, bovine, rat, mouse, rabbit

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References

ACTH1-17 is a more potent agonist at the human MC1 receptor than alpha-MSH.

Cell Mol Bio . 1999 Nov 01 ; 45(7) 1029 | DOI : 10644006

  • M. Tsatmali
  • et al

Modulation of the human hair follicle pigmentary unit by corticotropin-releasing hormone and urocortin peptides

FASEB J . 2006 May 01 ; 20(7) 882 | DOI : https://doi.org/10.1096/fj.05-5257com

  • S. Kauser
  • et al