Peptides

ACTH (1-24), human

  • Cat.Number : AS-20613
  • Availability :
    In stock

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The neuropeptide ACTH (adenocorticotropin; amino acids 1-39) is the natural cleavage product from POMC (proopimelanocortin) processing; however, the first 24-amino acid sequence from the carboxyl end, ACTH (1-24) has full biological activity of the (1-39) peptide. Both ACTH (1-24) and (1-39) possess neurotropic activity.

Specifications

Chemistry
Sequence one letter code
  • SYSMEHFRWGKPVGKKRRPVKVYP
Sequence three letter code
  • H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-tyr-pro-OH
CAS registry number
  • 16960-16-0
Molecular Formula
  • C136H210N40O31S
Molecular Mass/ Weight
  • 2933.6
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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Citations

Triggering and Visualizing the Aggregation and Fusion of Lipid Membranes in Microfluidic Chambers.

Biophys J. . 2006 Apr 14 ; 91(1) 233 | DOI : 10.1529/biophysj.105.076398

  • DJ. Estes
  • et al

Inhibition of a secreted glutamic peptidase prevents growth of the fungus Talaromyces emersonii

J Biol Chem. . 2008 Aug 07 ; 283(43) 29186 | DOI : 10.1074/jbc.M802366200

  • AJ. O'Donoghue
  • et al

A homogeneous enzyme fragment complementation-based β-arrestin translocation assay for high-throughput screening of G-protein-coupled receptors

J Biomol Screen. . 2008 Jul 25 ; 13(8) 737 | DOI : 10.1177/1087057108321531

  • X. Zhao
  • et al