IMG-EN-AS-60250-1-01.jpg
Peptides

Beta-Amyloid (1-33) - 1 mg

$486.00
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  • Cat.Number : AS-60250-1
  • Availability :
    In production

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Purified metalloendopeptidase cleaves the Gly33-Leu34 bond of Alzheimer Aß (1-40) peptide producing soluble 1-33 and 34-40 fragments of Aß (1-40) without any neurotoxic effects.

Specifications

Chemistry
Sequence one letter code
  • DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIG
Sequence three letter code
  • H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-OH
Molecular Formula
  • C164H242N46O51
Molecular Mass/ Weight
  • 3674.2
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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References

A new brain metalloendopeptidase which degrades the Alzheimer beta-amyloid 1-40 peptide producing soluble fragments without neurotoxic effects

Braz. J. Med. Biol. Res. . 1997 Oct 01 ; 30(10) 1153 | DOI : 10.1590/s0100-879x1997001000002

  • K. Carvalho
  • et al

Cerebrospinal Fluid Profile of Amyloid β Peptides in Patients with Alzheimer’s Disease Determined by Protein Biochip Technology

Neurodegenerative Dis . 2004 Jan 01 ; 1 231 | DOI : https://doi.org/10.1159/000080991

  • A. Maddalena
  • et al