Peptides

Beta-Amyloid (1-9) - 1 mg

  • Cat.Number : AS-61970
  • Availability :
    In stock

Quantity

This is the N-terminal fragment of b-Amyloid peptide amino acids 1 to 9. Omission of residues 1 to 9 from the full-length Alzheimer's b-Amyloid peptide 1 to 40 does not prevent the peptide from forming amyloid fibrils or eliminate fibril polymorphism. This b-Amyloid peptide fragment contains a functional B cell epitope, but lacks known T cell epitopes, which makes it an attractive candidate for the development of b-Amyloid vaccine that lacks the potential to induce autoimmune encephalitis.

Specifications

Chemistry
Sequence one letter code
  • DAEFRHDSG
Sequence three letter code
  • H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-OH
Molecular Formula
  • C42H60N14O17
Molecular Mass/ Weight
  • 1033.1
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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Beta-Amyloid (1-42)

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References

Papillomavirus-Like Particles Are an Effective Platform for Amyloid-β Immunization in Rabbits and Transgenic Mice

J Immunol . 2006 Aug 15 ; 177(4) 2662 | DOI : https://doi.org/10.4049/jimmunol.177.4.2662

  • E. Zamora
  • et al

Polymorphic Fibril Formation by Residues 10–40 of the Alzheimer’s β-Amyloid Peptide

Biophys J . 2006 Jun 15 ; 90(12) 4618 | DOI : https://doi.org/10.1529/biophysj.105.076927

  • A. Paravastu
  • et al