IMG-EN-AS-62897-01.jpg
Peptides

Beta-Amyloid (16-22) - 1 mg

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  • Cat.Number : AS-62897
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This is a short fragment of the b-Amyloid peptide containing two aromatic phenylalanine residues. Short peptide models have provided novel insight into the mechanistic issues of amyloid formation. This heptapeptide fragment has the capacity of forming typical amyloid fibrils in vitro. Aromatic interactions are important in many cases of amyloid formation.

Specifications

Chemistry
Sequence one letter code
  • KLVFFAE
Sequence three letter code
  • H-Lys-Leu-Val-Phe-Phe-Ala-Glu-OH
Molecular Formula
  • C43H64N8O10
Molecular Mass/ Weight
  • 853.1
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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References

Amyloid Fibril Formation by Aβ16-22, a Seven-Residue Fragment of the Alzheimer's β-Amyloid Peptide, and Structural Characterization by Solid State NMR

Biochem . 2000 Oct 14 ; 39(45) 13748 | DOI : https://doi.org/10.1021/bi0011330

  • JJ. Balbach
  • et al

Mechanisms of amyloid fibril self-assembly and inhibition

FEBS J. . 2005 Dec 01 ; 272(23) 5971 | DOI : https://doi.org/10.1111/j.1742-4658.2005.05022.x

  • E. Gazit