Beta-Amyloid (2-42)
- Cat.Number : AS-29909-01
- Manufacturer Ref. :
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This peptide is beta-amyloid (1-42) N-terminally truncated. It was shown that supplementing the media with N-terminally truncated Abeta (2-40) and (2-42) induce the phagocytosis of polystyrene particles by primary human monocytes. N-terminally truncated Aβ(x–42) induced the phagocytosis of PSPs significantly more effectively than did Aβ(x–40).
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Citations
N-truncation and pyroglutaminylation enhances the opsonizing capacity of Aβ-peptides and facilitates phagocytosis by macrophages and microglia.
Brain Behav Immun . 2014 May 27 ; 41 116 | DOI : 10.1016/j.bbi.2014.05.003.
- M. Condic
References
Elevation of β-Amyloid Peptide 2–42 in Sporadic and Familial Alzheimer's Disease and Its Generation in PS1 Knockout Cells
J Biol Chem . 2001 Nov 01 ; 276(46) 42645 | DOI : https://doi.org/10.1074/jbc.M102790200
- J. Wiltfang
- et al