Beta-Amyloid (22-42) - 1 mg
- Cat.Number : AS-61972
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This is the hydrophobic C-terminal fragment of b-Amyloid peptide amino acids 22 to 42.
Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.
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Citations
Alkylated dihydroxybenzoic acid as a MALDI matrix additive for hydrophobic peptide analysis.
Anal Chem . 2012 Apr 16 ; 84(9) 4237 | DOI : 10.1021/ac300540r
- Y. Fukuyama