Biotin-beta-Amyloid (25-35) - 1 mg
- Cat.Number : AS-62451
- Manufacturer Ref. :
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This peptide is amino acids 25 to 35 fragment of the ß-amyloid biotinylated at C-terminus. This peptide possesses many of the characteristics of the full-length ß-amyloid peptide, including an amphiphilic nature and an ability to aggregate, and can serve as a model system to study the conformational changes involved in Alzheimer's disease. Aggregates of ß-amyloid (25–35) have been shown to possess the neurotrophic and neurotoxic properties of their full-length counterparts and there is evidence that the monomeric form of the peptide may itself be cytotoxic.
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References
Effects of Solvent on the Structure of the Alzheimer Amyloid-β(25–35) Peptide
Biophys . 2006 Sep 01 ; 91(5) 1638 | DOI : https://doi.org/10.1529/biophysj.105.079186
- G. Wei
- J. Shea