Peptides

Biotin-LC-beta-Amyloid (1-42)

$175.00
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  • Cat.Number : AS-24641-01
  • Availability :
    In stock

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Size

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This biotinylated Aß(1-42) contains an 6-carbon long chain (LC) to provide more accessibility for avidin attachment.

Specifications

Chemistry
Sequence one letter code
  • Biotin-LC-DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Sequence three letter code
  • Biotin-LC-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH
CAS registry number
  • 1872440-40-8
Molecular Formula
  • C219H336N58O63S2
Molecular Mass/ Weight
  • 4853.9
Modification
Conjugation type
  • Biotins
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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Citations

Microglia constitute a barrier that prevents neurotoxic protofibrillar ​Aβ42 hotspots around plaques

Nat Commun. . 2015 Jan 29 ; 6 6176 | DOI : 10.1038/ncomms7176

  • C. Condello

A novel Aβ-fibrinogen interaction inhibitor rescues altered thrombosis and cognitive decline in Alzheimer’s disease mice.

J Exp Med . 2014 May 12 ; 211(6) 1049 | DOI : 10.1084/jem.20131751.

  • HJ. Ahn

N-truncation and pyroglutaminylation enhances the opsonizing capacity of Aβ-peptides and facilitates phagocytosis by macrophages and microglia.

Brain Behav Immun . 2014 May 27 ; 41 116 | DOI : 10.1016/j.bbi.2014.05.003.

  • M. Condic

Protection against β-Amyloid-induced Apoptosis by Peptides Interacting with β-Amyloid.

J Biol Chem . 2007 Aug 30 ; 283 6616 | DOI : 10.1074/jbc.M705558200

  • TJ. Nelson
  • DL. Alkon

Competitive electrochemical immunosensor for amyloid-beta 1-42 detection based on gold nanostructurated screen-printed carbon electrodes.

Sensors Actuators B: Chem . 2014 Oct 01 ; 201 567 | DOI : 10.1016/j.snb.2014.05.044.

  • EC. Rama

Protection against beta-amyloid induced apoptosis by peptides interacting with beta-amyloid.

J Biol Chem . 2007 Aug 30 ; 282(43) 31238 | DOI : 10.1074/jbc.M705558200 (2007).

  • TJ. Nelson
  • DL. Alkon