IMG-EN-AS-65577-01.jpg
Peptides

biotin-Neurogranin (48-76), mouse - 1 mg

$447.00
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  • Cat.Number : AS-65577
  • Availability :
    In production

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Neurogranin is a post synaptic protein that is expressed in dendritic cytoplasm. It modulates calcium-mediated signaling pathways and plays critical role in synaptic plasticity. Recently Neurogranin (48-76) was identified as a major neurogranin peptide fragment in human brain and it was found that patients with Alzheimer’s Disease have elevated levels of Neurogranin (48-76) in cerebrospinal fluid.

Specifications

Chemistry
Sequence one letter code
  • Biotin-SGECGRKGPGPGGPGGAGGARGGAGGGPS-OH
Sequence three letter code
  • biotin-Ser-Gly-Glu-Cys-Gly-Arg-Lys-Gly-Pro-Gly-Pro-Gly-Gly-Pro-Gly-Gly-Ala-Gly-Gly-Ala-Arg-Gly-Gly-Ala-Gly-Gly-Gly-Pro-Ser-OH
Molecular Formula
  • C101H162N38O36S2
Molecular Mass/ Weight
  • 2548.9
Modification
Conjugation type
  • Biotins
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • mouse

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References

C-terminal neurogranin is increased in cerebrospinal fluid but unchanged in plasma in Alzheimer's disease

Alzh and Dement . 2015 Dec 01 ; 11(12) 1461 | DOI : https://doi.org/10.1016/j.jalz.2015.05.012

  • A. De Vos
  • et al