IMG-EN-AS-65220-01.jpg
Peptides

ClearPoint™ beta-Amyloid (1-38), 13C-Phe & Ile - 0.05 mg

$152.00
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  • Cat.Number : AS-65220
  • Availability :
    In stock

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This peptide is beta-amyloid (1-38) with phenylalanine and isoleucine universally labeled with 13C. Ab is found in amyloid deposits of Alzheimer’s patients and is implicated in the pathogenesis of this disease.

Specifications

Chemistry
Sequence one letter code
  • DAEFRHDSGYEVHHQKLV-*F-*F-AEDVGSNKGA-*I-*I-GLMVGG *F=Phe(U-13C9), *I=Ile(U-13C6)
Sequence three letter code
  • H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-*Phe-*Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-**Ile-**Ile-Gly-Leu-Met-Val-Gly-Gly-OH *Phe(U-13C9); **Ile(U-13C6)
Molecular Formula
  • C184H277N51O56S
Molecular Mass/ Weight
  • 4161.9
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Application
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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References

Low-dose intraperitoneal Freund's adjuvant: Toxicity and immunogenicity in mice using an immunogen targeting amyloid-β peptide

Vaccine . 2006 Apr 01 ; 24(15) 3018 | DOI : https://doi.org/10.1016/j.vaccine.2005.10.046

  • J. Oscherwitz
  • et al