Peptides

ClearPoint™ beta-Amyloid (1-38), 13C-Phe & Ile - 0.05 mg

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  • Cat.Number : AS-65220
  • Availability :
    In stock

Quantity

This peptide is beta-amyloid (1-38) with phenylalanine and isoleucine universally labeled with 13C. Ab is found in amyloid deposits of Alzheimer’s patients and is implicated in the pathogenesis of this disease.

Notes: *F=Phe(U-13C9), *I=Ile(U-13C6), *Phe(U-13C9), **Ile(U-13C6)

Specifications

Chemistry
Sequence one letter code
  • DAEFRHDSGYEVHHQKLV-*F-*F-AEDVGSNKGA-*I-*I-GLMVGG
Sequence three letter code
  • H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-*Phe-*Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-**Ile-**Ile-Gly-Leu-Met-Val-Gly-Gly-OH
Molecular Formula
  • C184H277N51O56S
Molecular Mass/ Weight
  • 4161.9
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Application
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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References

Low-dose intraperitoneal Freund's adjuvant: Toxicity and immunogenicity in mice using an immunogen targeting amyloid-β peptide

Vaccine . 2006 Apr 01 ; 24(15) 3018 | DOI : https://doi.org/10.1016/j.vaccine.2005.10.046

  • J. Oscherwitz
  • et al