Peptides

Cys(Npys)-TAT (47-57), FAM-labeled - 1 mg

$315.00
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  • Cat.Number : AS-61213
  • Availability :
    In stock

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This peptide corresponds to the protein transduction domain of the TAT protein and is synthesized with an activated cysteine residue C(Npys), wherein Npys is 3-Nitro-2-pyridinesulfenyl group and is used for activating S of cysteine and for rapid reaction when a thiol group is introduced. This is synthesized with C(Npys) at the N-terminus for applications requiring specific conjugation reactions and has a fluorophore labeled with FAM having Abs/Em=494/518 nm. This kind of modification has been used to render this peptide as a cell penetrating and carrier peptide applicable in conjugation studies.

Specifications

Chemistry
Sequence one letter code
  • C(Npys)YGRKKRRQRRR-K(FAM)-NH2
Sequence three letter code
  • Cys(Npys)-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Lys(FAM)-NH2
Molecular Formula
  • C99H148N38O23S2
Molecular Mass/ Weight
  • 2302.6
Properties
Absorbance (nm)
  • 494
Emission (nm)
  • 518
Modification
Conjugation type
  • Fluorescent dyes
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C Protected from light
Activity
Biomarker Target
Detection Method
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • HIV

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Citations

Single molecule sensitive multivalent polyethylene glycol probes for RNA imaging.

Bioconj Chem . 2010 Feb 08 ; 21(3) 483 | DOI : 10.1021/bc9003876.

  • A. Lifland

References

ɛPKC confers acute tolerance to cerebral ischemic reperfusion injury

Neurosci lett. . 2008 Aug 15 ; 441(1) 120 | DOI : https://doi.org/10.1016/j.neulet.2008.05.080

  • R. Bright
  • et al

Cellular Uptake of Antisense Morpholino Oligomers Conjugated to Arginine-Rich Peptides

Bioconj Chem. . 2004 Feb 28 ; 15(2) 290 | DOI : 10.1021/bc034221g

  • HM. Moultin
  • et al