IMG-EN-AS-62068-01.jpg
Peptides

Glucagon-Like Peptide-2, GLP-2 (1-34), human - 1 mg

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  • Cat.Number : AS-62068
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    In stock

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Glucagon-like peptide-2 (GLP-2) promotes nutrient absorption via expansion of the mucosal epithelium by stimulation of crypt cell proliferation and inhibition of apoptosis in the small intestine. It also reduces epithelial permeability, and decreases meal-stimulated gastric acid secretion and gastrointestinal motility. GLP-2 promotes the expansion of the intestinal epithelium through stimulation of the GLP-2 receptor, a member of the glucagon-secretin G protein-coupled receptor superfamily.

Specifications

Chemistry
Sequence one letter code
  • HADGSFSDEMNTILDNLAARDFINWLIQTKITDR
Sequence three letter code
  • H-His-Ala-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp-Arg-OH
CAS registry number
  • 99120-49-7
Molecular Formula
  • C171H266N48O56S
Molecular Mass/ Weight
  • 3922.6
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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References

Identification of Glucagon-like Peptide-2 (GLP-2)-activated Signaling Pathways in Baby Hamster Kidney Fibroblasts Expressing the Rat GLP-2 Receptor

JBC . 1999 Oct 22 ; 274 30459 | DOI : 10.1074/jbc.274.43.30459

  • B. Yusta
  • et al

Biological actions and therapeutic potential of the glucagon-like peptides

Gastroenterol . 2002 Feb 01 ; 122(2) 531 | DOI : https://doi.org/10.1053/gast.2002.31068

  • D. Drucker
  • et al