IMG-EN-AS-63704-01.jpg
Peptides

[Gly21]-beta-Amyloid (1-42), Dutch Mutation - 0.5 mg

$347.00
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  • Cat.Number : AS-63704
  • Availability :
    In stock

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Several mutations in the beta amyloid precursor gene cause autosomal dominant Alzheimer's Disease in a number of kindreds. Amond them, the A21G Flemish mutation is unique as it shows a low tendency to aggregation, while deposits progressively appear in the vessel walls. In addition, the brain deposits are prefereably composed of A-beta 1-40 rather than A beta 1-42, in oppostiion to the other familial AD.

Specifications

Chemistry
Sequence one letter code
  • DAEFRHDSGYEVHHQKLVFFGEDVGSNKGAIIGLMVGGVVIA
Sequence three letter code
  • H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Gly-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH
Molecular Formula
  • C202H309N55O60S
Molecular Mass/ Weight
  • 4500.4
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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