IMG-EN-AS-65208-1-01.jpg
Peptides

[Lys(Ac)12]-Histone H4 (1-25)-GSGSK(Biotin) - 1 mg

$410.00
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  • Cat.Number : AS-65208-1
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    In stock

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This peptide is histone H4 (1-25) with acetylation at Lys12. It is biotinylated through a C-terminal GSGSK linker. Lys12 acetylation is necessary for the methylation of Lys9 of histone H3 in the formation of heterochromatin. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.

Specifications

Chemistry
Sequence one letter code
  • SGRGKGGKGLG-K(Ac)-GGAKRHRKVLRDN-GSGSK(Biotin)
Sequence three letter code
  • H-Ser-Gly-Arg-Gly-Lys-Gly-Gly-Lys-Gly-Leu-Gly-Lys(Ac)-Gly-Gly-Ala-Lys-Arg-His-Arg-Lys-Val-Leu-Arg-Asp-Asn-Gly-Ser-Gly-Ser-Lys(Biotin)-OH
Molecular Mass/ Weight
  • 3274.9
Modification
Conjugation type
  • Biotins
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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References

The role of histone H2Av variant replacement and histone H4 acetylation in the establishment of Drosophila heterochromatin

Gene Dev . 2005 Jan 01 ; 19(1) 65 | DOI : 10.1101/gad.1259105

  • J. Swaminathan
  • et al