Peptides

[Lys(Me1)36]-Histone H3 (26-46)-K(Biotin) - 1 mg

$362.00
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  • Cat.Number : AS-64602-1
  • Availability :
    In stock

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This peptide is a synthetic peptide corresponding to amino acids 26 to 46 of Schizosaccharomyces octosporus histone H3. It is also monomethylated at lysine-36, followed by a biotinylated lysine. The methylation of histone H3 at lysine 36 (K36) has recently been shown to be associated with RNA polymerase II (Pol II) elongation in Saccharomyces cerevisiae. Histone methylation also plays a key role in the regulation of chromatin structure and function. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.

Specifications

Chemistry
Sequence one letter code
  • RKAAPATGGV-K(Me1)-KPHRYRPGTV-K(Biotin)
Sequence three letter code
  • H-Arg-Lys-Ala-Ala-Pro-Ala-Thr-Gly-Gly-Val-Lys(Me1)-Lys-Pro-His-Arg-Tyr-Arg-Pro-Gly-Thr-Val-Lys(BIOTIN)-OH
Molecular Mass/ Weight
  • 2616.2
Modification
Conjugation type
  • Biotins
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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Citations

Selective recognition of H3.1K36 dimethylation/H4K16 acetylation facilitates the regulation of all-trans-retinoic acid (ATRA)-responsive genes by putative chromatin reader ZMYND8

J. Biol. Chem. . 2015 Dec 11 ; 291(6) 2664 | DOI : 10.1074/jbc.M115.679985

  • S. Adhikary

References

The Yng1p Plant Homeodomain Finger Is a Methyl-Histone Binding Module That Recognizes Lysine 4-Methylated Histone H3

Mol Cell Biol . 2006 Nov 01 ; 26(21) 7871 | DOI : 10.1128/MCB.00573-06

  • D. Martin
  • et al