IMG-EN-AS-65439-1-01.jpg
Peptides

[Lys(Me3)79]-Histone H3(73-83) - 1 mg

$131.00
Check your price
  • Cat.Number : AS-65439-1
  • Availability :
    In stock

Alternative choices

Quantity

Add to wishlist Bulk Quote

This peptide is Histone H3 amino acid residues 73 to 83 tri-methylated at Lysine 79. Histone lysine methylation plays a role in transcriptional regulation. H3K79 can be methylated by Dot1 methyltransferase.

Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.

Specifications

Chemistry
Sequence one letter code
  • EIAQDF-K(Me3)-TDLR
Sequence three letter code
  • H-Glu-Ile-Ala-Gln-Asp-Phe-Lys(Me3)-Thr-Asp-Leu-Arg-OH
Molecular Mass/ Weight
  • 1378.6
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

Downloads

You may also be interested in the following product(s)

IMG-EN-AS-64989-1-01.jpg

[Lys(Ac)5/8/12/16]-Histone H4 (1-21)-GGK(Biotin) - 1 mg

Cat.Number : AS-64989-1
$473.00 Excl. Tax
IMG-EN-AS-61702-01.jpg

Histone H3 (1-21)-GGK(Biotin)-NH2 - 1 mg

Cat.Number : AS-61702
$282.00 Excl. Tax
IMG-EN-AS-64440-025-01.jpg

Histone H3 (21-44)-GK(Biotin)

Cat.Number : AS-64440-025
$147.00 Excl. Tax

References

Biotinylation of lysine method identifies acetylated histone H3 lysine 79 in Saccharomyces cerevisiae as a substrate for Sir2

PNAS . 2012 Apr 17 ; 109(16) E916 | DOI : https://doi.org/10.1073/pnas.1121471109

  • P. Bheda
  • et al