Peptides

NDP-MSH, 5-TAMRA-labeled - 1 mg

$447.00
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  • Cat.Number : AS-60564-1
  • Availability :
    In stock

Quantity

This NDP-MSH peptide is fluorescently (5-TAMRA)-labeled on the N-terminus. Abs/Em=544/572 nm. NDP-MSH is a synthetic analog of alpha-Melanotropin (a-MSH, a-melanocyte-stimulating hormone) in which Asp4 has been replaced with Norleucine and L-Phe with the D-isomer of Phe [Nle4D-Phe7] (NDP). NDP-MSH is a more potent in increasing pigmentation and decreasing UV damage in fair-skinned Caucasian volunteers.

Specifications

Chemistry
Sequence one letter code
  • 5-TMR-SYS-Nle-EHfRWGKPV-NH2
Sequence three letter code
  • 5-TMR-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2
Molecular Formula
  • C101H129N23O22
Molecular Mass/ Weight
  • 2017.3
Properties
Absorbance (nm)
  • 544
Emission (nm)
  • 572
Modification
Conjugation type
  • Fluorescent dyes
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C Protected from light
Activity
Biomarker Target
Detection Method
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Human, bovine, rat

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References

4-Norleucine, 7-D-phenylalanine-alpha-melanocyte-stimulating hormone: a highly potent alpha-melanotropin with ultralong biological activity

PNAS . 1980 Oct 01 ; 77(10) 5754 | DOI : https://doi.org/10.1073/pnas.77.10.5754

  • TK. Sawyer
  • et al

[Nle4-D-Phe7]-α-Melanocyte-Stimulating Hormone Significantly Increased Pigmentation and Decreased UV Damage in Fair-Skinned Caucasian Volunteers

J Invest Dermatol . 2006 Aug 01 ; 126(8) 1869 | DOI : https://doi.org/10.1038/sj.jid.5700317

  • RS. Barnetson
  • et al