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Peptides

Protease-Activated Receptor-1, PAR-1 Antagonist 1 - 1 mg

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  • Cat.Number : AS-65486
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The peptide YFLLRNP is an antagonist to thrombin and SFLLRNP (thrombin receptor agonist peptide) in human platelets. YFLLRNP can induce partial activation of human platelets, visible by shape change; but it is unable to fully activate the platelets.

Specifications

Chemistry
Sequence one letter code
  • YFLLRNP-OH
Sequence three letter code
  • Tyr-Phe-Leu-Leu-Arg-Asn-Pro-OH
CAS registry number
  • 149440-16-4
Molecular Formula
  • C45H67N11O10
Molecular Mass/ Weight
  • 922.1
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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References

A peptide ligand of the human thrombin receptor antagonizes alpha-thrombin and partially activates platelets

J Biol Chem . 1993 Jul 05 ; 268(19) 14322 | DOI : https://doi.org/10.1016/S0021-9258(19)85244-4

  • UB Rasmussen
  • et al