Scrambled-beta-Amyloid (1-42)
- Cat.Number : AS-25382
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Aß (1-40) together with Aß (1-42) are two major C-terminal variants of the Aß protein constituting the majority of Aßs. These undergo post-secretory aggregation and deposition in the Alzheimer’s disease brain. This peptide is the scrambled sequence of Abeta 1-42.
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Citations
Hypersensitivity of the hippocampal CA3 region to stress-induced neurodegeneration and amyloidogenesis in a rat model of surgical menopause
Brain . 2013 May 01 ; 136(Pt 5) 1432 | DOI : 10.1093/brain/awt046
- QG. Zhang
Amyloid beta dimers/trimers potently induce cofilin-actin rods that are inhibited by maintaining cofilin-phosphorylation
Mol Neurodegener . 2011 Jan 24 ; 6 10 | DOI : 10.1186/1750-1326-6-10
- RC. Davis
Gelsolin Restores A-Induced Alterations in Choroid Plexus Epithelium
J Biomed and Biotech . 2010 Jan 19 ; 2010 7 | DOI : http://dx.doi.org/10.1155/2010/805405
- T. Vargas
Mutant presenilin 1 increases the expression and activity of BACE1
JBC . 2009 Feb 05 ; 284 9027 | DOI : 10.1074/jbc.M805685200
- L. Giliberto
Spatial Memory Impairment Without Apoptosis Induced by the Combination of Beta-Amyloid Oligomers and Cerebral Ischemia Is Related to Decreased Acetylcholine Release in Rats
J Pharmacol Sci . 2007 Nov 13 ; 106 84 | DOI : 10.1254/jphs.fp0071648
- T. Watanabe
Gelsolin Restores Aβ-Induced Alterations in Choroid Plexus Epithelium
J Biomed Biotechnol . 2010 Mar 25 ; 2010 805405 | DOI : https://doi.org/10.1155/2010/805405
- T. Vargas
Aβ induces cell death by direct interaction with its cognate extracellular domain on APP (APP 597–624).
FASEB Journal. . 2006 Apr 24 ; 20(8) 1254 | DOI : https://doi.org/10.1096/fj.05-5032fje
- GM. Shaked
Spreading of neurodegenerative pathology via neuron-to-neuron transmission of β-amyloid
J Neurosci. . 2012 Jun 27 ; 32(26) 8767 | DOI : 10.1523/JNEUROSCI.0615-12.2012
- S. Nath
Interaction between 24-hydroxycholesterol, oxidative stress and amyloid-β in amplifying neuronal damage in Alzheimer’s disease: three partners in crime
Aging Cell. . 2011 Apr 05 ; 10(3) 403 | DOI : 10.1111/j.1474-9726.2011.00681.x
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Neprilysin protects against cerebral amyloid angiopathy and Aβ-induced degeneration of cerebrovascular smooth muscle cells
Brain Pathol. . 2011 Apr 03 ; 21(5) 594 | DOI : 10.1111/j.1750-3639.2011.00486.x
- J. Miners
Gelsolin restures Aβ-induced alterations in choroid plexus epithelium
J Biomed Biotechnol. . 2010 Mar 25 ; 2010 805405 | DOI : 10.1155/2010/805405
- T. Vargas
Protection of synapes against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Aβ oligomers
Proc Natl Acad Sci U S A. . 2009 Feb 02 ; 106(6) 1971 | DOI : 10.1073/pnas.0809158106
- FG. De Felice
Amyloid beta mediates memory formation
Learn Mem. . 2009 Mar 24 ; 16(4) 267 | DOI : 10.1101/lm.1310209
- A. Garcia-Osta
Myelin basic protein binds to and inhibits the fibrillar assembly of Aβ42 in vitro
Biochemistry . 2015 Mar 20 ; 48(22) 4720 | DOI : 10.1021/bi900037s
- M. Hoos
Abeta induces cell death by direct interaction with its cognate extracellular domain on APP (APP 597-624).
FASEB J. . 2006 Apr 24 ; 20(8) 1254 | DOI : 10.1096/fj.05-5032fje
- GM. Shaked
β -Secretase-Cleaved Amyloid Precursor Protein Accumulates at Actin Inclusions Induced in Neurons by Stress or Amyloid β : A Feedforward Mechanism for Alzheimer’s Disease
J Neurosci. . 2005 Dec 07 ; 25(49) 11313 | DOI : https://doi.org/10.1523/JNEUROSCI.3711-05.2005
- MT. Maloney
Amyloid-β Peptide Inhibits Activation of the Nitric Oxide/cGMP/cAMP-Responsive Element-Binding Protein Pathway during Hippocampal Synaptic Plasticity
J Neurosci. . 2005 Jul 20 ; 25(29) 6887 | DOI : 10.1523/JNEUROSCI.5291-04.2005
- D. Puzzo
In Vitro Studies of Flemish, Dutch, and Wild-Type β-Amyloid Provide Evidence for Two-Staged Neurotoxicity
Neurobiol Dis. . 2002 Nov 01 ; 11(2) 330 | DOI : 10.1006/nbdi.2002.0529
- S. Kumar-Singh
Modeling Alzheimer's disease immune therapy mechanisms: Interactions of human postmortem microglia with antibody-opsonized amyloid beta peptide
J Neurosci Res. . 2002 Nov 15 ; 70(4) 599 | DOI : 10.1002/jnr.10422
- LF. Lue
- DG. Walker