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Peptides

Spike protein (S1/S2) SARS-CoV-2 substrate - 0.1 mg

$256.00
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  • Cat.Number : AS-65600
  • Availability :
    In stock

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This peptide sequence represents a furin-like cleavage site of the Spike (S) protein of the SARS-CoV-2 virus. The S protein must be likely cleaved at two sites, S1/S2 and S2 for viral entry into host cell. The sequence at the S1/S2 junction which contains a polybasic cleavage site (RR?AR) represents the first cleavage site. This peptide has been labeled with QXL®520 and 5-FAM.

Specifications

Chemistry
Sequence one letter code
  • QXL®520-TNSPRRARSVAS-K(5-FAM)-NH2
Sequence three letter code
  • QXL®520-Thr-Asn-Ser-Pro-Arg-Arg-Ala-Arg-Ser-Val-Ala-Ser-Lys(5-FAM)-OH
Molecular Mass/ Weight
  • 2278.4
Properties
Absorbance (nm)
  • 490
Emission (nm)
  • 520
Modification
Conjugation type
  • Double dyes
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C Protected from light
Activity
Application
Biomarker Target
Detection Method
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • SARS-CoV-2

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References

The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade

Antiviral Res. . 2020 Apr 01 ; 176 104742 | DOI : https://doi.org/10.1016/j.antiviral.2020.104742

  • B. Coutard
  • et al