IMG-EN-AS-64984-01.jpg
Peptides

TAT-GluR23A Fusion Peptide - 1 mg

$141.00
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  • Cat.Number : AS-64984
  • Availability :
    In production

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This is the GluR23A sequence, a control inactive peptide used as a mutant counterpart to glutamate receptor endocytosis inhibitor (GluR23Y), connected to an 11 amino acid cell permeable HIV Trans-Activator of Transcription (TAT) protein transduction domain (PTD). GluR23A is derived from GluR23Y amino acids 869 to 877, with Ala substituted for Tyr, and thus lacking essential phosphorylation sites.

Specifications

Chemistry
Sequence one letter code
  • YGRKKRRQRRRAKEGANVAG
Sequence three letter code
  • H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Ala-Lys-Glu-Gly-Ala-Asn-Val-Ala-Gly-OH
Molecular Formula
  • C97H173N43O26
Molecular Mass/ Weight
  • 2357.8
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • HIV, Influenza

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References

Tyrosine phosphorylation of GluR2 is required for insulin-stimulated AMPA receptor endocytosis and LTD.

EMBO J . 2004 Feb 19 ; 23(5) 1040 | DOI : 10.1038/sj.emboj.7600126

  • G. Ahmadian
  • et al

α-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid Subtype Glutamate Receptor (AMPAR) Endocytosis Is Essential for N-Methyl-D-aspartate-induced Neuronal Apoptosis

JBC . 2004 Oct 01 ; 279 41267 | DOI : 10.1074/jbc.C400199200

  • Y. Wang
  • et al

Role of AMPA receptor trafficking in NMDA receptor‐dependent synaptic plasticity in the rat lateral amygdala

J Neurochem . 2008 Jul 04 ; 106 889 | DOI : https://doi.org/10.1111/j.1471-4159.2008.05461.x

  • S. Yu
  • et al