Peptides

TAT-NSF700 Fusion Peptide - 1 mg

$352.00
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  • Cat.Number : AS-62238
  • Availability :
    In stock

Quantity

This peptide is the N-Ethyl-maleimide-sensitive factor (NSF) inhibitor fusion polypeptide composed of 11-amino acid cell permeable HIV transactivating regulatory protein (TAT) domain fused to a 22 amino acid NSF domain. TAT-NSF700 inhibits thrombin-induced exocytosis of endothelial cells in a dose-responsive manner.

Specifications

Chemistry
Sequence one letter code
  • YGRKKRRQRRR-GGG-LLDYVPIGPRFSNLVLQALLVL
Sequence three letter code
  • H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Gly-Gly-Leu-Leu-Asp-Tyr-Val-Pro-Ile-Gly-Pro-Arg-Phe-Ser-Asn-Leu-Val-Leu-Gln-Ala-Leu-Leu-Val-Leu-OH
Molecular Mass/ Weight
  • 4167.2
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • HIV

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Citations

P2X4-Receptor-Mediated Synthesis and Release of Brain-Derived Neurotrophic Factor in Microglia Is Dependent on Calcium and p38-Mitogen-Activated Protein Kinase Activation

J Neurosci. . 2009 Mar 18 ; 29(11) 3518 | DOI : 10.1523/JNEUROSCI.5714-08.2009

  • T. Trang

A Novel Class of Fusion Polypeptides Inhibits Exocytosis

Mol Pharmacol. . 2004 Dec 17 ; 67(4) 1137 | DOI : 10.1124/mol.104.004275

  • K. Matsushita

A Novel Inhibitor of N-Ethylmaleimide-Sensitive Factor Decreases Leukocyte Trafficking and Peritonitis

J Pharmacol Exp Ther . 2005 Mar 18 ; 314(1) 155 | DOI : 10.1124/jpet.104.082529

  • CN. Morrell

References

A Novel Class of Fusion Polypeptides Inhibits Exocytosis

Mol Pharmacol . 2005 Apr 01 ; 67 1137 | DOI : https://doi.org/10.1124/mol.104.004275

  • K. Matsushita
  • et al