IMG-EN-AS-61978-01.jpg
Peptides

Beta-Amyloid (17-24) - 1 mg

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  • Cat.Number : AS-61978
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This peptide is b-Amyloid 17 to 24 amino acids fragment (human, mouse, rat). Several lines of evidence indicate that a region centering around positions 17 to 20 amino acids is important for b-Amyloid fibril formation. Destabilization of a helix covering residues 11–24, in particular residues 17–24, is critical for alpha-helix to b-strand conversion and fibril formation.

Specifications

Chemistry
Sequence one letter code
  • LVFFAEDV
Sequence three letter code
  • H-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-OH
Molecular Formula
  • C46H66N8O13
Molecular Mass/ Weight
  • 939.1
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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References

Stabilization of discordant helices in amyloid fibril-forming proteins

Prot. Sci. . 2004 May 01 ; 13(5) 1251 | DOI : https://doi.org/10.1110/ps.03442404

  • A. Päivio
  • et al