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Peptides  >  Histones  >  Histone H4 Peptides  >>  [Lys(Ac)16]-Histone H4 (1-20), H4K16(Ac)

Product Name [Lys(Ac)16] - Histone H4 (1 - 20), H4K16(Ac)
Size 1 mg
Catalog # AS-63687
US$ $181
Purity % Peak Area By HPLC ≥ 95%

This Histone 4 peptide is acetylated at lysine 16. Lysine 16 of H4 appears to be a unique target for acetylation. Studies in yeast clearly indicate that acetylation of H4 lysine 16 is an independent specific function in relation to gene transcription when compared to other histone acetylation sites. It was also observed that a human histone acetyltransferase complex showed strong specificity for H4K16 in chromatin and, RNAi-mediated knockdown experiments revealed that it is responsible for the majority of H4 acetylation at lysine 16 in the cell.

Storage -20C
References 1, Borra, MT. et al. Biochem. 43, 9877 (2004)
2, Smith ER. et al. Mol Cell Biol, 25(21):9175-9188.
Molecular Weight 2034.4
(One-Letter Code)
(Three-Letter Code)
H - Ser - Gly - Arg - Gly - Lys - Gly - Gly - Lys - Gly - Leu - Gly - Lys - Gly - Gly - Ala - Lys(Ac) - Arg - His - Arg - Lys - OH
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