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Peptides  >  Histones  >  Histone H3 Peptides  >>  [Lys(Me3)27-Histone H3 (23-34)-GGK(Biotin)
Product Name [Lys(Me3)27 - Histone H3 (23 - 34) - GGK(Biotin)
KAAR - K(Me3) - SAPATGGGG - K(Biotin)
Size 1 mg
Catalog # AS-65397
US$ $210
Purity % Peak Area By HPLC ≥ 95%
Description

This is histone H3 (23-34) trimethylated at Lys27 and biotinylated on the C-terminus through a GGK linker. Trimethylation of Lys27 promotes Polycomb protein (Pc)-chromatin association. This modification has also been shown to be associated with methylated CpG island genes in cancer cells. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
Storage -20°C
References Schlesinger, Y. et al. Nat Genet 39, 232 (2007); Zhang, X. et al. Nat Struct Mol Biol 14, 869 (2007); Min, J. et al. Genes Dev 17, 1823 (2003).
Molecular Weight 1624.9
Sequence
(One-Letter Code)		 KAAR-K(Me3)-SAPATGGGG-K(Biotin)
Sequence
(Three-Letter Code)		 H - Lys - Ala - Ala - Arg - Lys(Me3) - Ser - Ala - Pro - Ala - Thr - Gly - Gly - Gly - Gly - Lys(Biotin) - OH
     
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