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Peptides  >  SARS-CoV2/COVID-19 Peptides  >>  Spike protein (S1/S2) SARS-CoV-2 substrate

Product Name Spike protein (S1/S2) SARS - CoV - 2 substrate
QXL520 - TNSPRRARSVAS - K(5 - FAM) - NH2
Size 0.1 mg
Catalog # AS-65600
US$ $205
Purity >95%
Description

This peptide sequence represents a furin-like cleavage site of the Spike (S) protein of the SARS-CoV-2 virus. The S protein must be likely cleaved at two sites, S1/S2 and S2 for viral entry into host cell. The sequence at the S1/S2 junction which contains a polybasic cleavage site (RR↓AR) represents the first cleavage site.
This peptide has been labeled with QXL520 and 5-FAM.

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20 C
References Coutard B, et al. The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade. Antiviral Res. 2020 Apr;176:104742. doi: 10.1016/j.antiviral.2020.104742.
Molecular Weight 2278.4
Sequence
(One-Letter Code)
QXL520-TNSPRRARSVAS-K(5-FAM)-NH2
Sequence
(Three-Letter Code)
H - Thr - Asn - Ser - Pro - Arg - Arg - Ala - Arg - Ser - Val - Ala - Ser - Lys(5 - FAM) - OH
     
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