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Peptides  >  Anti-Inflammatory Peptides  >>  C5a Receptor Agonist, mouse, human

Product Name C5a Receptor Agonist, mouse, human
FKP - (D - Cha) - Cha - r
Size 1 mg
Catalog # 65121
US$ $77
Purity % Peak Area By HPLC ≥ 95%
Description

This peptide is derived from the C-terminus of the chemokine, complement fragment 5 anaphylatoxin (C5a). This peptide functions as a C5a receptor agonist. C5a is a plasma protein involved in cellular inflammatory processes by inducing chemotaxis, degranulation of leukocytes, increased vascular permeability, and cytokine production. The cyclohexylalanine at position 5 is crucial to agonist function. Arg at the last position is of the d-isomer.

Storage -20C
References Buck, E. et al. PNAS 102, 2719 (2005); Higginbottom, A. J Biol Chem 280, 17831 (2005).
Molecular Weight 853.1
Sequence
(One-Letter Code)
FKP-(D-Cha)-Cha-r
Sequence
(Three-Letter Code)
H - Phe - Lys - Pro - D - Cha - Cha - D - Arg - OH
     
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