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Peptides  >  Angiotensins and Related Peptides  >>  ClearPoint Angiotensin I, human, 13C and 15N labeled

Product Name ClearPoint Angiotensin I, human, 13C and 15N labeled
DR - V* - Y - I* - HPFHL [Val* = Val(U - 13C5,15N); Ile* = Ile(U - 13C6,15N)]
Size 0.1 mg
Catalog # 65140
US$ $77
Purity % Peak Area By HPLC ≥ 95%
Description

This peptide is angiontensin I (Ang I) with valine and isoleucine universally labeled with 13C and N. Ang I is a precursor to Ang II, which has been implicated in cardiovascular functions, cell proliferation, fibrosis, and apoptosis. The 10-mer Ang I peptide is converted to Ang II through the cleavage of the Phe8-His9 bond of Ang I by angiotensin-converting enzyme (ACE) or human chymase.

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20C
References Lundequist, A. et al. J Cell Biol 279, 32339 (2004). Subramaniam, S. et al. J Cell Biol 272, 2963 (1997).
Molecular Weight 1309.5
Sequence
(One-Letter Code)
DR-V*-Y-I*-HPFHL [Val* = Val(U-13C5,15N); Ile* = Ile(U-13C6,15N)]
Sequence
(Three-Letter Code)
H - Asp - Arg - Val* - Tyr - Ile* - His - Pro - Phe - His - Leu - OH [Val* = Val(U - 13C5,15N); Ile* = Ile(U - 13C6,15N)]
     
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