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Peptides  >  Cancer Research Peptides  >>  MUC1, tandem repeat fragment

Product Name MUC1, tandem repeat fragment
PDTRPAPGSTAPPAHGVTSA
Size 1 mg
Catalog # 61451
US$ $121
Purity % Peak Area By HPLC ≥ 95%
Description

This sequence is the hallmark of MUC1 mucin. MUC1 is a highly glycosylated type I transmembrane glycoprotein with a unique extracellular domain consisting of a variable number of tandem repeats (VNTR) of this 20 amino acid peptide It is overexpressed on the cell surface of many human adenocarcinomas and hematological malignancies, including multiple myeloma and B-cell lymphoma, making MUC1 broadly applicable target for immunotherapeutic strategies

Storage -20C
References Ref:: Brossart, P. et al. Blood 93, 4309 (1999); Wajchman, H. et al. Cancer Res 64, 1171 (2004)
Molecular Weight 1887
Sequence
(One-Letter Code)
PDTRPAPGSTAPPAHGVTSA
Sequence
(Three-Letter Code)
Pro - Asp - Thr - Arg - Pro - Ala - Pro - Gly - Ser - Thr - Ala - Pro - Pro - Ala - His - Gly - Val - Thr - Ser - Ala
     
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