Dye-Labeled β-Amyloid – full spectrum of possibilities


Combining one of the world’s largest collections of β-amyloid peptides with proprietary expertise in detection technology, AnaSpec offers an unmatched array of dye labeled β-amyloid peptides. Our full spectrum of fluorescent dyes ranges from classic dyes like 5-FAM and 5-TAMRA to AnaSpec’s proprietary HiLyte™ Fluor series of high-performance dyes. Discover the possibilities.


Figure 1. Absorption and emission spectrum of the different fluorophore-labeled Aß (1-42) peptides.



Figure 2. Staining pattern of HiLyte™ Fluor 488 labeled A
β (1-42) peptide on an AD (A) and a normal brain (B) sections; HiLyte™ Fluor 555 labeled Aβ (1-42) peptide on an AD (C) and a normal brain (D) sections. Images courtesy of Dr. Jian-Ping Guo in Dr. Patrick L. McGeer’s lab, University of British Columbia, Vancouver, Canada.

Table 1. Select listing of off-the-shelf GO® versions of our dye-labeled β-amyloid peptides featuring the 3 most studied β-amyloid peptides.Dyes are labeled on the N-terminus (e.g. HiLyte™ Fluor 488-Aβ) or on the C-terminus on the side chain of an additional lysine .

Product

Ex/Em (nm)

Aβ (1-28)

Aβ (1-40)

Aβ (1-42)

AMCA-Aβ

354/442

60460 (0.1 mg)

60460 (0.1 mg)

60475-01 (0.1 mg)

5-FAM-Aβ

494/521

60759-01 (0.1 mg)

60759 (0.5 mg)

23514-01 (0.1 mg)

23513-05 (0.5 mg)

23526-01 (0.1 mg)

23525-05 (0.5 mg)

5-FAM-Aβ (Scrambled)

494/521

60892 (0.1 mg)

5-FAM-Aβ-K(Biotin)

494/521

23597-01 (0.1 mg)

23596 (0.5 mg)

23599-01 (0.1 mg)

23598 (0.5 mg)

5-FAM-Aβ-K(5-FAM)-NH2

494/521

64445-01 (0.1 mg)

HiLyte™ Fluor 488-Aβ

503/528

60466-01 (0.1 mg)

60491-01 (0.1 mg)

60479-01 (0.1 mg)

HiLyte™ Fluor 488 Aβ(mouse/rat)

503/528

64572 (0.1 mg)

Aβ-K(HiLyte™ Fluor 488)

503/528

60982 (0.1 mg)

HiLyte™ Fluor 555-Aβ

551/567

60468-01 (0.1 mg)

60492-01 (0.1 mg)

60480-01 (0.1 mg)

5-TAMRA-Aβ

544/572

60461-01 (0.1 mg)

60488-01 (0.1 mg)

60476 (0.1 mg)

Sulforhodamine101-Aβ

583/601

60489 (0.1 mg)

62221 (0.1 mg

HiLyte™ Fluor TR-Aβ

584/607

60464-01 (0.1 mg)

60490-01 (0.1 mg)

HiLyte™ Fluor TR-Aβ(mouse/rat)

584/607

64572 (0.1 mg)

Aβ-K(HiLyte™ Fluor TR)

584/607

60745 (0.1 mg)

HiLyte™ Fluor 647-Aβ

649/674

60469 (0.1 mg)

60493 (0.1 mg)

64161 (0.1 mg)

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