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Peptides  >  Signal Transduction Peptides  >>  Transcriptional Intermediary Factor 2, Tif-2 (685-697)

Product Name Transcriptional Intermediary Factor 2, Tif - 2 (685 - 697)
EKHKILHRLLQDS
Size 1 mg
Catalog # 61994
US$ $83
Purity % Peak Area By HPLC ≥ 95%
Description

This 13-amino acid TIF2 peptide with a LxxLL motif is derived from the NR box2 region of TIF2 (SRC2–2). A short consensus motif, so-called nuclear receptor (NR) box, mediates ligand-dependent activation interaction function between nuclear receptors and their coregulators. This TIF2 peptide fragment is sufficient to interact with thyroid hormone ligand binding domain, TR-beta- LBD.

Storage -20°C
References Kong, E. et al. PNAS 102, 3593 (2005); Wärnmark, A., et al. J. Biol. Chem. 277, 21862 (2002); Darimont, B. et al. Genes Dev. 12, 3343 (1998).
Molecular Weight 1616.9
Sequence
(One-Letter Code)
EKHKILHRLLQDS
Sequence
(Three-Letter Code)
H - Glu - Lys - His - Lys - Ile - Leu - His - Arg - Leu - Leu - Gln - Asp - Ser - OH
     
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