This peptide is histone H2A (1-22) phosphorylated at Ser1, followed by a C-terminal GGK with biotinylation on the side chain of this Lys. Phosphorylated Ser1 increases during mitotic S and M phases in HeLa cells and may be associated with chromatin condensation and histone deposition. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
Bonenfant, D. et al. Mol Cell Proteomics5, 541 (2006); Barber, C. et al. Chromosoma112, 360 (2004).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - pSer - Gly - Arg - Gly - Lys - Gln - Gly - Gly - Lys - Ala - Arg - Ala - Lys - Ala - Lys - Ser - Arg - Ser - Ser - Arg - Ala - Gly - Gly - Gly - Lys(Biotin) - OH