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Peptides  >  GPCR Peptide Ligands  >  Orphanin  >>  Nociceptin (1-7), (Orphanin FQ, or OFQ/N) (1-7)

Product Name Nociceptin (1 - 7), (Orphanin FQ, or OFQ/N) (1 - 7)
FGGFTGA
Size 1 mg
Catalog # 62611
US$ $71
Description

This peptide is amino acids 1 to 7 fragment of nociceptin (orphanin FQ, OFQ/N). The complete OFQ/N sequence contains pairs of basic amino acids that might imply additional processing of the peptide to this OFQ/N 1 to 7 fragment. This truncated peptide is functionally active when administered in vivo producing analgesia that is reversed by opioid antagonists. The peptide shows no appreciable affinity for any of the traditional opioid receptors.

Storage -20C
References Mogil, J. and Pasternak, G. Pharmacol. Rev. 53, 381 (2001).
Molecular Weight 655.7
Sequence
(One-Letter Code)
FGGFTGA
Sequence
(Three-Letter Code)
H - Phe - Gly - Gly - Phe - Thr - Gly - Ala - OH
     
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