96 - well Overlapping Peptide Library Spike glycoprotein from SARS - CoV - 2
Spike glycoprotein from SARS-CoV-2: NCBI the RefSeq (YP_009724390.1) of 1273 aa
Peptide length: 15 aa, 9aa for the C-terminal peptide.
Gross peptide weight: not quantified
Synthesis scale: 5 µmol
Offset number: 7 aa
Format: lyophilized in 96-well plate (P-DW-20-C Axygen®)
Counter ion: TFA
QC validation: MALDI-TOF QC on 10 % of peptides
Coronavirus Spike glycoproteins mediate the virus attachment to host cell surface receptors and facilitate the virus entry by assisting fusion between viral and host cell membranes. They are composed of two subunits, S1 and S2. The Spike protein of SARS-CoV-2 harbors furin cleavage sites, one being located at the boundary between S1 and S2. Spike glycoproteins are extensively studied as targets for antibodies, vaccine candidates or protease inhibitors, as examples. We developed a peptide library spanning the entire Spike glycoprotein from SARS-CoV-2. The library is provided in a convenient 96-well plate format adapted for screening purposes.