Histone Peptides are GO


Histone Peptides are GO

AnaSpec, the world's largest provider of on-demand GO peptides is pleased to offer a wide selection of Histone H1, H2A, H2B, H3 and H4 peptides, especially the H3 peptides. The rapidly expanding Histone H3 GO Peptides include sequences that are acetylated, mono-, di- or tri-methylated, phosphorylated and biotinylated.

Chromatin exist either as the transcriptionally active euchromatin or as the transcriptionally repressed heterchromatin state.1 Post-translational modifications of histone "tails" (amino termini) have been implicated in the conversion between the two states. 1-2 Covalent modifications, such as acetylation, methylation and phosphorylation affect chromatin structure and exquisitely regulate gene expression.3-6 Histone hyperacetylation is correlated with increased transcription, whereas hypoacetylation correlates with transcriptional repression.5 In Histone H3, preferential methylation sites have been shown to be Lys4, Lys9, Lys27 and Lys36, with methylation generally leading to transcriptional suppression.3,7 Methylation of specific arginine residues in H3 has been shown to correlate with cell fate and potency.8 Phosphorylation at Ser10 (pSer10) is implicated in both transcription and cell division.9

H3 Peptide

Product

Size

Catalog #

Histone H3 (1 - 21), N - Terminal
ARTKQTARKSTGGKAPRKQLA

1 mg

61701

Histone H3 (1 - 21), Biotinylated
ARTKQTARKSTGGKAPRKQLA - GG - K(BIOTIN) - NH2

1 mg

61702

Histone H3 (1 - 21), FAM labeled NEW
ARTKQTARKSTGGKAPRKQLAGG - K(FAM) - NH2

1 mg

63824

Histone H3 (1 - 25), amide
ARTKQTARKSTGGKAPRKQLATKAA - NH2

1 mg

61703

Histone H3 (116136), C116136
KRVTIMPKDIQLARRIRGERA

1 mg

61704


Arg2, 8, 17 Modified H3 Peptides

Product

Size

Catalog #

[Arg(Me1)8] - Histone H3 (1 - 21) - K(biotin), H3R8(Me1), biotin labeled NEW
ARTKQTA - R(Me1) - KSTGGKAPRKQLA - K(Biotin) - NH2

1 mg

64607-1

[Arg(Me1)17] - Histone H3 (1 - 21) - GGK(Biotin), H3R17(Me1), biotin - labeled NEW
ARTKQTARKSTGGKAP - R(Me1) - KQLA - GGK(Biotin) - NH2

1 mg

64632-1



Lys4 Modified H3 Peptides

Product

Size

Catalog #

[Lys(Me1)4] - Histone H3 (1 - 10), H3K4(Me1) NEW
ART - K(Me1) - QTARKS

1 mg

64369-1

[Lys(Me2)4] - Histone H3 (1 - 10), H3K4(Me2) NEW
ART - K(Me2) - QTARKS

1 mg

64370-1

[Lys(Me3)4] - Histone H3 (1 - 10), H3K4(Me3) NEW
ART - K(Me3) - QTARKS

1 mg

64371-1

[Lys(Me1)4] - Histone H3 (1 - 21), H3K4(Me1) NEW
ART - K(Me1) - QTARKSTGGKAPRKQLA

1 mg

64459

[Lys(Me2)4] - Histone H3 (1 - 21), H3K4(Me2)
ART - K(Me2) - QTARKSTGGKAPRKQLA

1 mg

63677

[Lys(Me3)4] - Histone H3 (1 - 21), H3K4(Me3) NEW
ART - K(Me3) - QTARKSTGGKAPRKQLA

1 mg

64194

[Lys(Me3)4] - Histone H3 (1 - 25); H3K4(Me3) NEW
ART - K(Me3) - QTARKSTGGKAPRKQLATKAA - NH2

1 mg

64636-1

[Lys(Me1)4] - Histone H3 (1 - 21) - GGK(Biotin), H3K4(Me1), biotin - labeled NEW
ART - K(Me1) - QTARKSTGGKAPRKQLA - GGK(Biotin)

0.25 mg

1 mg

64355-025

64355-1

[Lys(Me2)4] - Histone H3 (1 - 21) - GGK(Biotin), H3K4(Me2), biotin - labeled NEW
ART - K(Me2) - QTARKSTGGKAPRKQLA - GGK(Biotin)

0.25 mg

1 mg

64356-025

64356-1

[Lys(Me3)4] - Histone H3 (1 - 21) - GGK(Biotin), H3K4(Me3), biotin - labeled NEW
ART - K(Me3) - QTARKSTGGKAPRKQLA - GGK(Biotin)

0.25 mg

1 mg

64357-025

64357-1

[Lys(Me3)4] - Histone H3 (1 - 21) - GGK(Biotin), H3K4(Me3), biotin labeled NEW
ART - K(Me3) - QTARKSTGGKAPRKQLA - GGK(Biotin) - NH2

1 mg

64192

Histone H3 (1 - 21), K4 di - methylated, H3K4(Me2), FAM labeled NEW
ART - K(Me2) - QTARKSTGGKAPRKQLAGG - K(FAM) - NH2

1 mg

63825


Lys9 Modified H3 Peptides

Product

Size

Catalog #

[Lys(Ac)9] - Histone H3 (1 - 20), H3K9(Ac)
ARTKQTAR - K(Ac) - STGGKAPRKQL

1 mg

63680

[Lys(Ac)9] - Histone H3 (1 - 21), H3K9(Ac) NEW
ARTKQTAR - K(Ac) - STGGKAPRKQLA

1 mg

64191

[Lys(Ac)9] - Histone H3 (1 - 21) - GGK(Biotin), H3K9(Ac), biotin - labeled NEW
ARTKQTAR - K(Ac) - STGGKAPRKQLA - GGK(Biotin)

0.25 mg

1 mg

64361-025

64361-1

[Lys(Ac)9] - Histone H3 (1 - 21) - NH2, H3K9(Ac), biotin - labeled, amide NEW
ARTKQTAR - K(Ac) - STGGKAPRKQLA - GGK(Biotin) - NH2

1 mg

64190

[Lys(Ac)9/14] - Histone H3 (1 - 21) - GGK(Biotin), H3K9/14(Ac), biotin - labeled NEW
ARTKQTAR - K(Ac) - STGG - K(Ac) - APRKQLA - GGK(Biotin)

0.25 mg

1 mg

64363-025

64363-1

[Lys(Ac)9] - Histone H3 (1 - 24), H3K9(Ac) NEW
ARTKQTAR - K(Ac) - STGGKAPRKQLATKA

1 mg

64453

[Lys(Me3)9] - Histone H3 (1 - 21), H3K9(Me3)
ARTKQTAR - K(Me3) - STGGKAPRKQLA

1 mg

64452

[Lys(Me1)9] - Histone H3 (1 - 21) - GGK(Biotin), H3K9(Me1), biotin -labeled NEW
ARTKQTAR - K(Me1) - STGGKAPRKQLA - GGK(Biotin)

0.25 mg

1 mg

64358-025

64358-1

[Lys(Me2)9] - Histone H3 (1 - 21) - GGK(Biotin), H3K9(Me2), biotin - labeled NEW
ARTKQTAR - K(Me2) - STGGKAPRKQLA - GGK(Biotin)

0.25 mg

1 mg

64359-025

64359-1

[Lys(Me3)9] - Histone H3 (1 - 21) - GGK(Biotin), H3K9(Me3), biotin - labeled NEW
ARTKQTAR - K(Me3) - STGGKAPRKQLA - GGK(Biotin)

0.25 mg

1 mg

64360-025

64360-1

[Lys(Me1)9] - Histone H3 (1 - 21) - GGK(Biotin); H3K9(Me1), biotin - labeled NEW
ARTKQTAR - K(Me1) - STGGKAPRKQLA - GGK(Biotin) - NH2

1 mg

64626-1

[Lys(Me2)9] - Histone H3 (1 - 21) - GGK(Biotin), H3K9(Me2), biotin labeled, amide NEW
ARTKQTAR - K(Me2) - STGGKAPRKQLA - GGK(Biotin) - NH2

1 mg

64627-1

[Lys(Me3)9] - Histone H3 (1 - 21) - GGK(Biotin), H3K9(Me3), biotin - labeled, amide
ARTKQTAR - K(Me3) - STGGKAPRKQLAGG - K(Biotin) - NH2

1 mg

64628-1

[Lys(Me2)9] - Histone H3 (1 - 21) - K(Biotin), H3K9(Me2), biotin - labeled NEW
ARTKQTAR - K(Me2) - STGGKAPRKQLA - K(Biotin)

1 mg

63678

[Lys(Me1)9] - Histone H3 (3 - 17), H3K9(Me1) NEW
TKQTAR - K(Me1) - STGGKAPR

1 mg

64372-1

[Lys(Me2)9] - Histone H3 (3 - 17), H3K9(Me2) NEW
TKQTAR - K(Me2) - STGGKAPR

1 mg

64373-1

[Lys(Me3)9] - Histone H3 (3 - 17), H3K9(Me3) NEW
TKQTAR - K(Me3) - STGGKAPR

1 mg

64374-1


Ser10 Modified H3 Peptides

Product

Size

Catalog #

[pSer10), Lys(Ac)14] - Histone H3 (1 - 21) - GGK(Biotin), biotin - labeled NEW
ARTKQTARK - pS - TGG - K(Ac) - APRKQLAGGK(Biotin)

0.25 mg

 

64364-025

 

[pSer10] - Histone H3 (1 - 21) - GGK(Biotin); H3pS10, biotin - labeled NEW
ARTKQTARK - pS - TGGKAPRKQLA - GGK(Biotin) - NH2

1 mg

64611-1


Lys14 Modified H3 Peptides

Product

Size

Catalog #

[Lys(Ac)14] - Histone H3 (1 - 19), H3K14(Ac)
ARTKQTARKSTGG - K(Ac) - APRKQ

1 mg

63682

[Lys(Ac)14] - Histone H3 (1 - 21) - GGK(Biotin), H3K14(Ac), biotin - labeled NEW
ARTKQTARKSTGG - K(Ac) - APRKQLA - GGK(Biotin)

0.25 mg

1 mg

64362-025

64362-1

[Lys(Ac)14] - Histone H3 (9 - 19), H3K14(Ac)
KSTGG - K(Ac) - APRKQ

1 mg

63681

[Lys(Ac)9/14] - Histone H3 (1 - 21) - GGK(Biotin), H3K9/14(Ac), biotin - labeled NEW
ARTKQTAR - K(Ac) - STGG - K(Ac) - APRKQLA - GGK(Biotin)

0.25 mg

1 mg

64363-025

64363-1

[pSer10), Lys(Ac)14] - Histone H3 (1 - 21) - GGK(Biotin), biotin - labeled NEW
ARTKQTARK - pS - TGG - K(Ac) - APRKQLAGGK(Biotin)

0.25 mg

 

64364-025

 


Lys18 Modified H3 Peptides

Product

Size

Catalog #

[Lys(Ac)18] - Histone 3 (1 - 21) - GGK(Biotin); H3K18(Ac), biotin - labeled NEW
ARTKQTARKSTGGKAPR - K(Ac) - QLA - GGK(Biotin) - NH2

1 mg

64638-1

[Lys(Me1)18] - Histone H3 (1 - 21) - GGK(Biotin), H3K18(Me1), biotin - labeled NEW
ARTKQTARKSTGGKAPR - K(Me1) - QLA - GGK(Biotin) - NH2

1 mg

64621-1

[Lys(Me2)18] - Histone H3 (1 - 21) - GGK(Biotin), H3K18(Me2), biotin - labeled NEW
ARTKQTARKSTGGKAPR - K(Me2) - QLA - GGK(Biotin) - NH2

1 mg

64620-1


Lys23 Modified H3 Peptides

Product

Size

Catalog #

[Lys(Me1)23] - Histone H3 (21 - 44) - GK(Biotin); H3K23(Me1), biotin - labeled NEW
AT - K(Me1) - AARKSAPSTGGVKKPHRYRPG - GK(Biotin) - NH2

1 mg

64617-1


Lys27 Modified H3 Peptides

Product

Size

Catalog #

[Lys(Ac)27] - Histone 3 (21 - 44) - GK(Biotin); H3K27(Ac), biotin - labeled NEW
ATKAAR - K(Ac) - SAPSTGGVKKPHRYRPG - GK(Biotin) - NH2

1 mg

64637-1

[Lys(Me1)27] - Histone H3 (21 - 44) - GK(Biotin), H3K27(Me1), biotin - labeled NEW
ATKAAR - K(Me1) - SAPATGGVKKPHRYRPG - GK(Biotin)

0.25 mg

1 mg

64365-025

64365-1

[Lys(Me2)27] - Histone H3 (21 - 44) - GK(Biotin), H3K27(Me2), biotin - labeled NEW
ATKAAR - K(Me2) - SAPATGGVKKPHRYRPG - GK(Biotin)

0.25 mg

1 mg

64366-025

64366-1

[Lys(Me3)27] - Histone H3 (21 - 44) - GK(Biotin), H3K27(Me3), biotin - labeled NEW
ATKAAR - K(Me3) - SAPATGGVKKPHRYRPG - GK(Biotin)

0.25 mg

1 mg

64367-025

64367-1

[Lys(Me1)27] - Histone H3 (23 - 34), H3K27(Me1) NEW
KAAR - K(Me1) - SAPATGG

1 mg

64376-1

[Lys(Me2)27] - Histone H3 (23 - 34), H3K27(Me2) NEW
KAAR - K(Me2) - SAPATGG

1 mg

64377-1

[Lys(Me3)27] - Histone H3 (23 - 34), H3K27(Me3) NEW
KAAR - K(Me3) - SAPATGG

1 mg

64378-1


Lys36 Modified H3 Peptides

Product

Size

Catalog #

[Lys(Me1)36] - Histone H3 (21 - 44) - GK(Biotin), H3K36(Me1), biotin - labeled NEW
ATKAARKSAPATGGV - K(Me1) - KPHRYRPG - GK(Biotin)

0.25 mg

1 mg

64368-025

64368-1

[Lys(Me2)36] - Histone H3 (21 - 44) - GK(Biotin), H3K36(Me2), biotin - labeled NEW
ATKAARKSAPATGGV - K(Me2) - KPHRYRPG - GK(Biotin)

0.25 mg

1 mg

64442-025

64442-1

[Lys(Me3)36] - Histone H3 (21 - 44) - GK(Biotin), H3K36(Me3), biotin - labeled NEW
ATKAARKSAPATGGV - K(Me3) - KPHRYRPG - GK(Biotin)

0.25 mg

1 mg

64441-025

64441-1

[Lys(Me1)36] - Histone H3 (26 - 46) - K(Biotin), H3K36(Me1) NEW
RKAAPATGGV - K(Me1) - KPHRYRPGTV - K(BIOTIN)

1 mg

64602-1

[Lys(Me2)36] - Histone H3 (26 - 46), H3K36(Me2) NEW
RKAAPATGGV - K(Me2) - KPHRYRPGTV - K(BIOTIN)

1 mg

64601-1

[Lys(Me1)36] - Histone H3 (31 - 41), H3K36(Me1) NEW
STGGV - K(Me1) - KPHRY

1 mg

64379-1

[Lys(Me2)36] - Histone H3 (31 - 41), H3K36(Me2) NEW
STGGV - K(Me2) - KPHRY

1 mg

64380-1

[Lys(Me3)36] - Histone H3 (31 - 41), H3K36(Me3) NEW
STGGV - K(Me3) - KPHRY

1 mg

64381-1


Lys79 Modified H3 Peptides

Product

Size

Catalog #

[Lys(Me2)79] - Histone H3 (69 - 89) - K(Biotin), H3K79(Me2), biotin - labeled NEW
RLVREIAQDF - K(Me2) - TDLRFQSSAV - K(Biotin)

0.25 mg

64544

[Lys(Me3)79] - Histone H3 (69 - 89) - K(Biotin), H3K79(Me3), biotin - labeled NEW
RLVREIAQDF - K(Me3) - TDLRFQSSAV - K(biotin)

0.25 mg

64545-025


H1 Peptides

Product

Size

Catalog #

Histone H1 - derived Peptide
GGGPATPKKAKKL

1 mg

61761

Histone H1 - derived Peptide, FAM - labeled
5 - FAM - GGGPATPKKAKKL

1 mg

61762


H2A Peptides

Product

Size

Catalog #

Histone H2A (1 - 20)
SGRGKQGGKARAKAKTRSSR

1 mg

63676

Histone H2A (1 - 22) - GK(Biotin) NEW
SGRGKQGGKARAKAKSRSSRA - GGK(Biotin) - NH2

1 mg

64639-1


H2B Peptides

Product

Size

Catalog #

Histone H2B (21 - 41) - GGK(Biotin), biotin labeled NEW
AQKKDGKKRKRSRKESYSIYV - GGK(Biotin)

1 mg

64385-1


H4 Peptides

Product

Size

Catalog #

Histone H4 (1 - 7), N - Terminal
SGRGKGG

1 mg

62754

Histone H4 (1 - 20), PRMT7 Substrate, M1
SGRGKGGKGLGKGGAKRHRK - NH2

1 mg

62498

Histone H4 (1 - 21), p300/CBP Substrate
SGRGKGGKGLGKGGAKRHRKV

1 mg

62499

Histone H4 (1 - 21) - GGK(Biotin)
Ac SGRGKGGKGLGKGGAKRHRKV - GGK(Biotin)

1 mg

62555

[Lys(Ac)5] - Histone H4 (1 - 20), H4K5(Ac)
SGRG - K(Ac) - GGKGLGKGGAKRHRK

1 mg

63683

[Lys(Ac)8] - Histone H4 (1 - 20), H4K8(Ac)
SGRGKGG - K(Ac) - GLGKGGAKRHRK

1 mg

63684

[Lys(Ac)12] - Histone H4 (1 - 20), H4K12(Ac)
SGRGKGGKGLG - K(Ac) - GGAKRHRK

1 mg

63685

[Lys(Ac)16] - Histone H4 (1 - 20), H4K16(Ac)
SGRGKGGKGLGKGGA - K(Ac) - RHRK

1 mg

63687

[Lys(Me1)20] - Histone H4 (1 - 23) - GGK(Biotin), H3K20(Me1), biotin - labeled NEW
SGRGKGGKGLGKGGAKRHR - K(Me1) - VLR - GGK(Biotin) - NH2

1 mg

64623-1

[Lys(Me3)20] - Histone H4 (1 - 23) - GGK(Biotin), H3K20(Me3), biotin - labeled NEW
SGRGKGGKGLGKGGAKRHR - K(Me3) - VLR - GGK(Biotin) - NH2

1 mg

64625-1

[Lys(Me2)20] - Histone H4 (1 - 23) - GGK(Biotin), H3K20(Me2), biotin - labeled NEW
SGRGKGGKGLGKGGAKRHR - K(Me2) - VLR - GGK(Biotin) NH2

1 mg

64624-1

References:

1. Grunstein, M. et al. J. Cell Sci. Suppl. 19, 29 (1995).
2. Strahl, BR and CD Allis, Nature 403, 41 (2000).
3. Strahl, BD. et al. Proc. Natl. Acad. Sci. 96, 14967 (1999).
4. Jenuwein, T. and CD. Allis Science 293, 1074 (2001).
5. Sterner, DE. et al. Microbiol. Mol. Biol. Rev. 64, 435 (2000).
6. Lachner, M. et al. J. Cell Sci. 116, 2117 (2003).
7. Nishioka, K. et al. Genes & Dev. 16, 479 (2002).
8. Torres-Padilla, M-E. et al. Nature 445, 214 (2007).
9. Prigent, C. and S. Dimitrov, J. Cell Sci. 116, 3677 (2003).