Dermcidin-1L (DCD-1L) is a 48-amino acid antimicrobial peptide (AMP) with a Leu residue on the C-terminus. It is expressed in eccrine sweat glands, secreted into sweat, and transported to the epidermal surface. Unlike most AMPs, which are cationic, DCD has a net negative charge.
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Ser - Ser - Leu - Leu - Glu - Lys - Gly - Leu - Asp - Gly - Ala - Lys - Lys - Ala - Val - Gly - Gly - Leu - Gly - Lys - Leu - Gly - Lys - Asp - Ala - Val - Glu - Asp - Leu - Glu - Ser - Val - Gly - Lys - Gly - Ala - Val - His - Asp - Val - Lys - Asp - Val - Leu - Asp - Ser - Val - Leu - OH